Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382080 | 0.81 | LMNA (0.34) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL14361944 | 0.79 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL11404507 | 0.78 | DPP4 (0.33) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL9384434 | 0.78 | LMNA (0.32) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL23670668 | 0.77 | — | — | |
| SCHEMBL19285582 | 0.77 | — | — | |
| SCHEMBL3337623 | 0.77 | LMNA (0.39) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL6584107 | 0.77 | — | — | |
| SCHEMBL9034127 | 0.74 | LCK (0.60) | LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL3898588 | 0.74 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116840958-A | Solvent polymer holographic grating and preparation method thereof | 江西联昊光电有限公司 | 2023-10-03 | — | — | CN | disclosed |
| US-5990341-A | Diastereoselective synthesis hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |
| US-5587514-A | Diastereoselective synthesis of hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1995014655-A1 | DIASTEREOSELECTIVE SYNTHESIS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES | EMORY UNIVERSITY (US) | 1995-06-01 | — | — | WO | disclosed |
| US-4644012-A | WITH 3-PHENYL-4H-1-BENZOPYRAN-4-ONE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| EP-0146921-A2 | Method for treating osteoporosis | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |