Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898588 | 0.81 | LMNA (0.40) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL14361944 | 0.81 | LMNA (0.40) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL7497247 | 0.80 | CA12 (0.44) | LMNAALDH1A1DPP4MEN1KMT2A | |
| SCHEMBL11632818 | 0.78 | LMNA (0.32) | LMNAALDH1A1 | |
| SCHEMBL3200366 | 0.78 | LMNA (0.42) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL8475923 | 0.77 | LMNA (0.37) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL11767508 | 0.77 | DPP4 (0.42) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL18098236 | 0.76 | LMNA (0.40) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL1964784 | 0.76 | LMNA (0.40) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL17652005 | 0.76 | LMNA (0.40) | LMNAALDH1A1MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56152446-A | — | — | None | — | — | JP | disclosed |
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | SOOCHOW UNIVERSITY (CN) | 2018-07-19 | — | — | US | disclosed |
| WO-2017215110-A1 | SYNTHETIC METHOD FOR ASYMMETRICAL THIOETHER | 苏州大学 | 2017-12-21 | — | — | WO | disclosed |
| EP-2146574-B1 | PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N, N-DIETHYL-2-( - NAPHTHOXY) PROPIONAMIDE | UPL LTD (IN) | 2015-11-04 | — | — | EP | disclosed |
| US-8309765-B2 | Process for manufacture of high purity D-(−)-N,N-diethyl-2-(α-naphthoxy) propionamide | UNITED PHOSPHORUS LIMITED (IN) | 2012-11-13 | — | — | US | disclosed |
| US-20100144532-A1 | PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N,N-DIETHYL-2-(alpha-NAPHTHOXY) PROPIONAMIDE | UPL LIMITED (IN) | 2010-06-10 | — | — | US | disclosed |
| US-5108489-A | HERBICIDAL DISUBSTITUTED NAPHTHALENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| EP-0109311-B1 | N,N-DIALKYL-2-(4'-SUBSTITUTED-1'-NAPHTHOXY)PROPIONAMIDES | STAUFFER CHEMICAL COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |
| US-4548641-A | PREEMERGENCE HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0109311-A1 | N,N-dialkyl-2-(4'-substituted-1'-naphthoxy)propionamides | STAUFFER CHEMICAL COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| JP-S56152446-A | ALPHA-SUBSTITUTED FATTY ACID AMID AND THEIR SALT | NIPPON NOHYAKU CO LTD | 1981-11-26 | — | — | JP | disclosed |
| US-4051182-A | Process for the manufacture of α-chloropropionyl chloride | STAUFFER CHEMICAL COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-3998880-A | Production of N,N-diethyl 2(α-naphthoxy)propionamide | STAUFFER CHEMICAL COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | STS, TST, SCLY | LMNA 4580/4885ALDH1A1 842/4885MMP1 1464/4885 |
| US-20100144532-A1 | PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N,N-DIETHYL-2-(alpha-NAPHTHOXY) PROPIONAMIDE | DNPH1, NAAA, DDT | LMNA 244/4885ALDH1A1 501/4885MMP1 4183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.