Phthalic Acid

Phthalic Acid

SCHEMBL8475937

CCOC(C)=O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
ALDH1A1 P00352 8/20 0.56
HSD17B10 Q99714 5/20 0.56
LMNA P02545 3/20 0.56
ALOX15 P16050 1/20 0.56
KDM4E B2RXH2 4/20 0.53
HPGD P15428 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ESR1 P03372 1/20 0.53
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
HMGB1 P09429 1/20 0.53
GGT1 P19440 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
BLM P54132 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluic Acid SCHEMBL28309919 0.91 TSHR (0.53) TSHRALDH1A1HSD17B10LMNAALOX15
Toluic Acid SCHEMBL27925543 0.89 TSHR (0.52) TSHRALDH1A1HSD17B10LMNAALOX15
Ethyl Acetate SCHEMBL30185781 0.86 ALDH1A1 (0.57) TSHRALDH1A1HSD17B10LMNAKDM4E
Phthalic Acid SCHEMBL28743573 0.86 MEN1 (0.61) TSHRALDH1A1HSD17B10LMNAALOX15
Phthalic Acid SCHEMBL28246162 0.86 TSHR (0.61) TSHRALDH1A1HSD17B10LMNAALOX15
Toluic Acid SCHEMBL27794019 0.85 ALDH1A1 (0.47) TSHRALDH1A1HSD17B10LMNAKDM4E
Acetic Acid SCHEMBL28481489 0.85 TSHR (0.78) TSHRALDH1A1HSD17B10LMNAALOX15
Diethyl Phthalate SCHEMBL1237247 0.85 TSHR (0.78) TSHRALDH1A1HSD17B10LMNAALOX15
Diethyl Phthalate SCHEMBL28196637 0.84 TSHR (0.84) TSHRALDH1A1HSD17B10LMNAALOX15
SCHEMBL29628800 0.84 TSHR (0.84) TSHRALDH1A1HSD17B10LMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493312-A Method for plating gallium oxide film on inner wall of glass capillary tube for thermometer 东阿阿华医疗科技有限公司 2021-10-12 CN claimed
CN-113493312-A Method for plating gallium oxide film on inner wall of glass capillary tube for thermometer 东阿阿华医疗科技有限公司 2021-10-12 CN disclosed
CN-107303278-B HC-1119 solid dispersion and preparation method thereof 成都海创药业有限公司 2020-11-13 CN disclosed
US-10010862-B2 Hydrophilic magnetic resin with high specific area, preparation method therefor and application method thereof for rapidly extracting phthalates in water body NANJING UNIVERSITY (CN) 2018-07-03 US disclosed
US-20160220982-A1 Hydrophilic Magnetic Resin with High Specific Area, Preparation Method Therefor and Application Method Thereof for Rapidly Extracting Phthalates in Water Body NANJING UNIVERSITY (CN) 2016-08-04 US disclosed
CN-103371925-A Oily methyl oil for human body SHANGHAI DONGSHEN ELECTRONIC TECHNOLOGY CO LTD 2013-10-30 CN disclosed
US-5939244-A YELLOW IMAGE DYE FORMING COUPLER EASTMAN KODAK COMPANY (US) 1999-08-17 US disclosed