Phthalic Acid

Phthalic Acid

SCHEMBL28246162

CCOC(=O)OCC.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
ALDH1A1 P00352 6/20 0.58
ALOX15 P16050 1/20 0.58
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HSD17B10 Q99714 2/20 0.52
GAA P10253 1/20 0.50
LMNA P02545 1/20 0.49
NPC1 O15118 1/20 0.49
MYC P01106 2/20 0.48
AKR1C3 P42330 1/20 0.48
NR4A1 P22736 1/20 0.48
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
HPGD P15428 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28212139 0.90 KDM4E (0.56) TSHRALDH1A1ALOX15MEN1KMT2A
Salicylic Acid SCHEMBL27819454 0.89 ALDH1A1 (0.64) TSHRALDH1A1ALOX15MEN1KMT2A
Phthalic Acid SCHEMBL28743573 0.88 MEN1 (0.61) TSHRALDH1A1ALOX15MEN1KMT2A
SCHEMBL29628800 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10
Diethyl Phthalate SCHEMBL28274022 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10
Phthalic Acid SCHEMBL8475937 0.86 TSHR (0.59) TSHRALDH1A1ALOX15MEN1KMT2A
SCHEMBL50234 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10
Phthalic Acid SCHEMBL9132525 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10
Diethyl Phthalate SCHEMBL9132522 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10
Phthalic Acid SCHEMBL6234815 0.86 TSHR (0.84) TSHRALDH1A1ALOX15KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108666501-A A kind of preparation method for the p-aramid fiber membrane for polymer that can be used for lithium ion battery produced with method of electrostatic spinning 烟台泰和新材料股份有限公司 2018-10-16 CN disclosed