Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476145 | 0.89 | LMNA (0.46) | HSD17B10KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL8714576 | 0.86 | KMT2A (0.47) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8716448 | 0.86 | KMT2A (0.64) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8479040 | 0.84 | KMT2A (0.44) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL9013742 | 0.83 | MEN1 (0.46) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8475297 | 0.82 | GAA (0.64) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8479673 | 0.77 | GAA (0.52) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8479289 | 0.75 | KMT2A (0.70) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8475279 | 0.75 | KMT2A (0.60) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL8711149 | 0.74 | KMT2A (0.59) | KMT2AMEN1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861517-A | INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEINS LEVELS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |