Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 10/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753418 | 1.00 | AGTR1 (0.57) | AGTR1LTB4R2ABCB11GP6KDM4E | |
| SCHEMBL8476139 | 1.00 | AGTR1 (0.57) | AGTR1LTB4R2ABCB11GP6KDM4E | |
| SCHEMBL2441623 | 0.91 | AGTR1 (0.47) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2445912 | 0.91 | AGTR1 (0.56) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL1808771 | 0.89 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL29561367 | 0.89 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2032 | 0.89 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2033 | 0.89 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL21125779 | 0.89 | AGTR1 (0.59) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL21125780 | 0.89 | AGTR1 (0.59) | AGTR1LTB4R2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101450917-B | Valsartan synthesis method | ZHEJIANG HISUN PHARM CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-101450917-A | Valsartan synthesis method | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-103923028-A | Preparation method of valsartan | QINGDAO XUEJIE CHEMICALS CO LTD | 2014-07-16 | — | — | CN | disclosed |
| CN-101450917-B | Valsartan synthesis method | ZHEJIANG HISUN PHARM CO LTD | 2012-07-11 | — | — | CN | disclosed |
| CN-101450917-A | Valsartan synthesis method | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2009-06-10 | — | — | CN | disclosed |
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |