Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | CTRC | Q99895 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673341 | 0.87 | F2 (0.50) | F2CTRCTP53MAPT | |
| SCHEMBL5676152 | 0.83 | ALDH1A1 (0.48) | TP53MAPTLMNA | |
| SCHEMBL8476274 | 0.80 | ALDH1A1 (0.44) | TP53MAPTLMNA | |
| SCHEMBL5673644 | 0.79 | F2 (0.70) | F2PRSS2CTRC | |
| SCHEMBL8476636 | 0.78 | GLA (0.43) | TP53MAPTLMNA | |
| SCHEMBL5674442 | 0.77 | F2 (0.70) | F2PRSS2CTRC | |
| SCHEMBL5674392 | 0.77 | F2 (0.66) | F2PRSS2CTRC | |
| SCHEMBL5674291 | 0.77 | F2 (0.74) | F2PRSS2CTRC | |
| Nitric Acid SCHEMBL5675984 | 0.76 | F2 (0.43) | F2PRSS2CTRC | |
| SCHEMBL5676136 | 0.76 | F2 (0.72) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |