Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476274 | 0.83 | ALDH1A1 (0.44) | GLAALDH1A1MAPTTSHRLMNA | |
| SCHEMBL5676152 | 0.82 | ALDH1A1 (0.48) | GLAALDH1A1MAPTTSHRLMNA | |
| SCHEMBL5673341 | 0.81 | F2 (0.50) | GLAALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL8481232 | 0.79 | F2 (0.49) | — | |
| SCHEMBL8476269 | 0.78 | F2 (0.51) | MAPTLMNATP53 | |
| SCHEMBL8480305 | 0.78 | F2 (0.53) | — | |
| SCHEMBL8479909 | 0.77 | F2 (0.53) | — | |
| SCHEMBL8481882 | 0.77 | F2 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8476682 | 0.77 | F2 (0.56) | — | |
| SCHEMBL8482323 | 0.75 | F2 (0.53) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |