Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474442 | 0.92 | ATM (0.50) | KDM4EALDH1A1POLBALOX15CNR2 | |
| SCHEMBL8475107 | 0.91 | KDM4E (0.45) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8472201 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1POLBALOX15PTGER4 | |
| SCHEMBL8476475 | 0.88 | CNR1 (0.49) | MEN1KMT2AKDM4EALDH1A1CNR2 | |
| Hydrochloric Acid SCHEMBL8472504 | 0.86 | CNR2 (0.48) | MEN1KMT2ACNR2CNR1 | |
| SCHEMBL8472285 | 0.85 | ALDH1A1 (0.52) | MEN1KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL8475123 | 0.83 | CNR1 (0.51) | ALDH1A1CNR2CNR1PTGER4 | |
| SCHEMBL8472597 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL8472630 | 0.83 | POLB (0.45) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8899446 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |