Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472597 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8472285 | 0.96 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8475932 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8472213 | 0.92 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8476897 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8476848 | 0.90 | KDM4E (0.48) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8472229 | 0.89 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8472594 | 0.87 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8472527 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPK1HPGD | |
| SCHEMBL8476217 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |