Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483180 | 0.89 | F2 (0.38) | F2ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL8480761 | 0.82 | F2 (0.41) | F2 | |
| SCHEMBL8477625 | 0.82 | ALPL (0.48) | F2ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL8477016 | 0.80 | F2 (0.37) | F2ALDH1A1MAPTMEP1BCTRC | |
| SCHEMBL8481232 | 0.79 | F2 (0.49) | F2CTRC | |
| SCHEMBL8481882 | 0.79 | F2 (0.52) | F2ALDH1A1SMN1; SMN2CTRCCASP1 | |
| SCHEMBL5672913 | 0.78 | KMT2A (0.42) | F2ALDH1A1MAPTMEP1BKMT2A | |
| SCHEMBL5672979 | 0.78 | F2 (0.46) | F2CTRC | |
| SCHEMBL8477586 | 0.77 | F2 (0.55) | F2CTRCCASP1 | |
| SCHEMBL8480305 | 0.77 | F2 (0.53) | F2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |