Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | CTRC | Q99895 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482817 | 0.89 | F2 (0.39) | F2ALDH1A1MAPTPRSS2CTRC | |
| SCHEMBL8479862 | 0.82 | ALPL (0.48) | F2ALDH1A1 | |
| SCHEMBL8482545 | 0.81 | F2 (0.44) | F2 | |
| SCHEMBL8476368 | 0.80 | F2 (0.33) | F2MEP1BALDH1A1MAPTCTRC | |
| SCHEMBL5672913 | 0.80 | KMT2A (0.42) | F2MEP1BKAT6AALDH1A1MAPT | |
| SCHEMBL8481378 | 0.80 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL8479188 | 0.79 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL8477571 | 0.78 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL5674299 | 0.78 | F2 (0.47) | F2PRSS2CTRC | |
| SCHEMBL8477294 | 0.78 | F2 (0.57) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |