Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389499 | 0.84 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL8470092 | 0.83 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL7389934 | 0.82 | GPR119 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL22322044 | 0.81 | GPR119 (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL32669085 | 0.79 | GPR119 (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL23086729 | 0.77 | GPR119 (0.54) | CHEK2GPR119PDE4BPDE4APDE4C | |
| SCHEMBL1894331 | 0.77 | USP30 (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL6190259 | 0.77 | GPR119 (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL7389137 | 0.77 | GPR119 (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGCHEK2 | |
| SCHEMBL1134253 | 0.76 | GPR119 (0.55) | CHEK2GPR119PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |