Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134253 | 0.93 | GPR119 (0.55) | GPR119CHEK2HRH3PDE4BTRIM24 | |
| SCHEMBL22322044 | 0.88 | GPR119 (0.57) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL32669085 | 0.86 | GPR119 (0.50) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL6189661 | 0.84 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL7389499 | 0.83 | PIK3CD (0.47) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL7389137 | 0.83 | GPR119 (0.55) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL6190259 | 0.83 | GPR119 (0.55) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL8476399 | 0.82 | PIK3CD (0.46) | GPR119USP30CHEK2PIK3CDPIK3CA | |
| SCHEMBL3342813 | 0.82 | GPR119 (0.55) | GPR119CHEK2HRH3PDE4BALDH1A1 | |
| SCHEMBL7480141 | 0.82 | GPR119 (0.48) | GPR119USP30CHEK2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |