Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140247 | 0.66 | ESR1 (0.42) | ESR1ESR2AR | |
| SCHEMBL29557461 | 0.63 | ESR1 (0.74) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL2862424 | 0.63 | ESR1 (0.74) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL12917725 | 0.62 | ESR1 (0.56) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL8474283 | 0.62 | ESR1 (0.37) | ESR1ESR2AR | |
| SCHEMBL16063499 | 0.59 | ESR1 (0.38) | ESR1ESR2AR | |
| SCHEMBL1513816 | 0.59 | ESR1 (0.61) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL15596256 | 0.58 | ESR1 (0.61) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL26364228 | 0.57 | ESR1 (0.59) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL26111049 | 0.57 | ESR1 (0.59) | ESR1ESR2ARHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861359-A | WHEAT, SOYBEANS, CORN; PRE- AND POSTEMERGENCE HERBICIDES | FMC CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1997005115-A1 | HERBICIDAL PHENYLMETHOXYPHENYL HETEROCYCLES | FMC CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |