Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479530 | 0.92 | PTGS1 (0.42) | PTGS1PTGS2HTR6PI4KBHPGD | |
| SCHEMBL8473864 | 0.88 | PTGS1 (0.42) | PTGS1PTGS2HTR6ALDH1A1LMNA | |
| SCHEMBL8478783 | 0.87 | PTGS2 (0.42) | PTGS1PTGS2HTR6ALDH1A1LMNA | |
| SCHEMBL8480051 | 0.87 | PTGS1 (0.45) | PTGS1PTGS2HTR6PI4KBALDH1A1 | |
| SCHEMBL8475048 | 0.86 | PTGS2 (0.41) | PTGS1PTGS2HTR6ALDH1A1LMNA | |
| SCHEMBL8474255 | 0.85 | PTGS1 (0.42) | PTGS1PTGS2HTR6KDM4EALDH1A1 | |
| SCHEMBL8478349 | 0.84 | PTGS1 (0.43) | PTGS1PTGS2HTR6PI4KBALDH1A1 | |
| SCHEMBL6169842 | 0.83 | PTGS2 (0.47) | PTGS1PTGS2HTR6ALDH1A1KMT2A | |
| SCHEMBL8478641 | 0.83 | PTGS2 (0.44) | PTGS1PTGS2HTR6HPGDKDM4E | |
| SCHEMBL8478256 | 0.81 | PTGS2 (0.42) | PTGS1PTGS2HTR6SLC40A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |