Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472430 | 0.94 | ESR1 (0.71) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL7110896 | 0.92 | ESR1 (0.69) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL8478033 | 0.92 | ESR1 (0.68) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL8476709 | 0.91 | ESR1 (0.67) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL7107851 | 0.89 | ESR1 (0.79) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL6592276 | 0.87 | ESR1 (0.76) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL4660156 | 0.87 | ESR1 (0.79) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL8472437 | 0.87 | ESR1 (0.73) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| SCHEMBL7105763 | 0.86 | ESR1 (0.72) | ESR1ESR2MCHR1LTA4HPSMB1 | |
| Hydrochloric Acid SCHEMBL7153807 | 0.85 | ESR1 (0.71) | ESR1ESR2MCHR1LTA4HPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958916-A | FOR INHIBITING BONE LOSS OR BONE RESORPTION | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |