Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676185 | 0.92 | L3MBTL1 (0.44) | F2SMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL8481720 | 0.90 | GAA (0.50) | F2POLBSMN1; SMN2TSHRLMNA | |
| SCHEMBL8480689 | 0.90 | SMN1; SMN2 (0.47) | F2SMN1; SMN2TSHRKMT2AGAA | |
| SCHEMBL8479188 | 0.88 | F2 (0.56) | F2 | |
| SCHEMBL8482817 | 0.87 | F2 (0.39) | F2SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL8481749 | 0.82 | F2 (0.46) | F2 | |
| SCHEMBL8477325 | 0.80 | F2 (0.48) | F2POLBSMN1; SMN2CASP1LMNA | |
| SCHEMBL5674364 | 0.80 | F2 (0.49) | F2POLBSMN1; SMN2TSHRCASP1 | |
| SCHEMBL8481378 | 0.80 | F2 (0.56) | F2 | |
| SCHEMBL8479211 | 0.80 | F2 (0.54) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |