Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476641 | 0.90 | F2 (0.50) | SMN1; SMN2TSHRF2GAAKMT2A | |
| SCHEMBL5676185 | 0.89 | L3MBTL1 (0.44) | SMN1; SMN2F2KMT2A | |
| SCHEMBL8481720 | 0.87 | GAA (0.50) | SMN1; SMN2TSHRF2GAAWDR5 | |
| SCHEMBL8479188 | 0.85 | F2 (0.56) | F2 | |
| SCHEMBL8477096 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2GLATSHRF2GAA | |
| SCHEMBL5672814 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2GLATSHRF2GAA | |
| SCHEMBL5675847 | 0.79 | F2 (0.54) | SMN1; SMN2GLATSHRF2PKM | |
| SCHEMBL8479180 | 0.79 | F2 (0.44) | F2 | |
| SCHEMBL8481378 | 0.77 | F2 (0.56) | F2 | |
| SCHEMBL8482817 | 0.77 | F2 (0.39) | SMN1; SMN2F2KDM4EKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |