Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472669 | 0.86 | GPR88 (0.43) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8472465 | 0.86 | MEN1 (0.45) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8476781 | 0.85 | EPHX2 (0.48) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8472656 | 0.84 | MEN1 (0.56) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8475715 | 0.83 | MEN1 (0.44) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8471933 | 0.83 | MAPK1 (0.37) | GPR88GHSR | |
| SCHEMBL8472278 | 0.83 | POLB (0.43) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8472570 | 0.82 | MEN1 (0.44) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| SCHEMBL8472240 | 0.77 | SMN1; SMN2 (0.42) | MEN1POLBAPOBEC3ACASP6KMT2A | |
| Hydrochloric Acid SCHEMBL8472761 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |