Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476781 | 0.86 | EPHX2 (0.48) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8476135 | 0.85 | POLB (0.48) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8475163 | 0.83 | MEN1 (0.50) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8476779 | 0.83 | MEN1 (0.40) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472187 | 0.82 | MEN1 (0.62) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472895 | 0.81 | HTR6 (0.55) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472024 | 0.80 | AURKA (0.41) | AURKAAURKBHRH3MCHR1ESR1 | |
| SCHEMBL8473549 | 0.78 | POLB (0.45) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8471948 | 0.74 | SMN1; SMN2 (0.47) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8473687 | 0.73 | LTA4H (0.44) | MEN1KMT2APOLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |