Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.49 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847681 | 0.80 | DNMT1 (0.55) | S1PR1S1PR3HTR2CHTR2BDNMT1 | |
| SCHEMBL846054 | 0.78 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL11938472 | 0.71 | PKM (0.47) | ITKAURKAMAP4K4CHEK2PRKCG | |
| SCHEMBL846204 | 0.71 | TRPV1 (0.64) | S1PR1S1PR3MEN1PABPC1KMT2A | |
| SCHEMBL3037483 | 0.71 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL8819827 | 0.70 | PKM (0.59) | MEN1KMT2AACHE | |
| SCHEMBL5274067 | 0.69 | SRD5A2 (0.53) | MEN1KMT2AITKAURKAMAP4K4 | |
| SCHEMBL6911011 | 0.68 | MEN1 (0.59) | MEN1PABPC1KMT2AEIF4HHDAC6 | |
| SCHEMBL12240483 | 0.68 | DNMT1 (0.71) | S1PR1S1PR3HTR2CHTR2BDNMT1 | |
| SCHEMBL1749860 | 0.68 | SRD5A2 (0.50) | MEN1KMT2AITKAURKAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |