Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL3 | P20749 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472211 | 0.96 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL8472594 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2PARP1HPGD | |
| SCHEMBL8474453 | 0.91 | LMNA (0.49) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| Hydrochloric Acid SCHEMBL8476314 | 0.88 | KDM4E (0.38) | KDM4EGAAHSD17B10ALOX15MAPK1 | |
| SCHEMBL8476848 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| Hydrochloric Acid SCHEMBL8474659 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL8475954 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1POLBGAAHPGD | |
| SCHEMBL8476838 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL8472229 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2POLBGAA | |
| Hydrochloric Acid SCHEMBL8474178 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |