Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472211 | 0.92 | KDM4E (0.45) | LMNATACR2KDM4EALDH1A1GAA | |
| SCHEMBL8476841 | 0.91 | KDM4E (0.42) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL8479145 | 0.90 | HTR2C (0.42) | LMNAKMT2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL8472339 | 0.89 | SMN1; SMN2 (0.40) | LMNAMAPTPKMKDM4EALDH1A1 | |
| SCHEMBL8474454 | 0.89 | LMNA (0.53) | LMNAMAPTPKMTACR2KDM4E | |
| SCHEMBL8472594 | 0.88 | KDM4E (0.44) | LMNAKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8474450 | 0.86 | LMNA (0.47) | LMNAMAPTPKMTACR2KDM4E | |
| SCHEMBL8477078 | 0.86 | HTR2C (0.42) | KDM4EHTR2CHTR2B | |
| SCHEMBL8472003 | 0.85 | HTR2C (0.43) | LMNAKDM4EALDH1A1HTR2CHTR2B | |
| SCHEMBL8477279 | 0.85 | LMNA (0.51) | LMNAMAPTPKMTACR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |