SCHEMBL8477048

SCHEMBL8477048

C=C(C)C(=O)Nc1cccc(C)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
HSD17B10 Q99714 1/20 0.68
KMT2A Q03164 6/20 0.57
MEN1 O00255 4/20 0.57
RXFP1 Q9HBX9 1/20 0.57
GAA P10253 1/20 0.56
KCNK3 O14649 1/20 0.53
KCNH2 Q12809 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 3/20 0.53
FAAH O00519 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
JAK3 P52333 1/20 0.52
CYP1A2 P05177 1/20 0.51
SAE1 Q9UBE0 1/20 0.51
UBA2 Q9UBT2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1098272 0.89 TDP1 (0.79) TDP1HSD17B10RXFP1KCNK3KCNH2
SCHEMBL21567990 0.87 HSD17B10 (0.74) HSD17B10KMT2AMEN1RXFP1GAA
SCHEMBL31598546 0.84 HSD17B10 (0.61) TDP1HSD17B10KMT2AMEN1RXFP1
SCHEMBL5421444 0.82 TDP1 (1.00) TDP1KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL216958 0.82 TDP1 (0.70) TDP1HSD17B10KMT2AMEN1RXFP1
SCHEMBL17400848 0.81 GPR35 (0.74) HSD17B10KMT2AMEN1RXFP1GAA
SCHEMBL18499179 0.81 HSD17B10 (0.66) HSD17B10KMT2AMEN1RXFP1GAA
SCHEMBL12133 0.81 HSD17B10 (1.00) TDP1HSD17B10KMT2AMEN1RXFP1
SCHEMBL30703669 0.81 HSD17B10 (1.00) TDP1HSD17B10KMT2AMEN1RXFP1
SCHEMBL23053168 0.81 TDP1 (0.68) TDP1HSD17B10RXFP1ALDH1A1JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3936556-A Marking of articles BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
EP-3557324-A1 POSITIVE LITHOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-10-23 EP disclosed
US-5998091-A COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-3936556-A Marking of articles BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed