Benzotriazole

Benzotriazole

SCHEMBL8477124

CO.c1ccc2[nH]nnc2c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 2/20 0.37
PKM P14618 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ABCB11 O95342 1/20 0.37
TP53 P04637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37
IDO1 P14902 1/20 0.35
DDAH1 O94760 1/20 0.35
POLB P06746 2/20 0.34
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
SLC9A1 P19634 1/20 0.34
KEAP1 Q14145 1/20 0.34
MASP2 O00187 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotriazole SCHEMBL28306454 0.95 ALDH1A1 (0.39) L3MBTL1ALDH1A1NPC1PKMRAB9A
Benzotriazole SCHEMBL22165676 0.93 ALDH1A1 (0.38) ALDH1A1NPC1PKMRAB9ASMN1; SMN2
Benzotriazole SCHEMBL28212495 0.93 NPC1 (0.38) L3MBTL1ALDH1A1NPC1PKMRAB9A
Benzotriazole SCHEMBL29381270 0.93
Benzotriazole SCHEMBL6088869 0.93 ALDH1A1 (0.41) ALDH1A1NPC1PKMRAB9ASMN1; SMN2
Benzotriazole SCHEMBL8956 0.93
Benzotriazole SCHEMBL10790175 0.91 ALDH1A1 (0.37) ALDH1A1NPC1PKMRAB9ASMN1; SMN2
Benzotriazole SCHEMBL4734294 0.91 ALDH1A1 (0.39) L3MBTL1ALDH1A1NPC1PKMRAB9A
Benzotriazole SCHEMBL10347824 0.91 ALDH1A1 (0.37) ALDH1A1NPC1PKMRAB9ASMN1; SMN2
Benzotriazole SCHEMBL27304957 0.91 ALDH1A1 (0.37) ALDH1A1NPC1PKMRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557750-A Method for preparing zeolite-like metal framework material containing benzotriazole ligand UNIV NANKAI 2015-04-29 CN disclosed
CN-102229820-B Denatured methanol diesel and blending process thereof LI ZHENFA 2013-08-14 CN disclosed
CN-102229820-A Denatured methanol diesel and blending process thereof ZHENFA LI 2011-11-02 CN disclosed
CN-1993446-B Red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC 2010-07-21 CN disclosed
CN-101044115-A Piperidines and related compounds for treatment of alzheimer's disease MERCK SHARP & DOHME (GB) 2007-09-26 CN disclosed
CN-1993446-A Red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC (KR) 2007-07-04 CN disclosed
US-5972961-A ANTIISCHEMIC AGENTS; ANTICONVULSANTS; HEADACHES; SEXUAL DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-10-26 US disclosed