Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 3/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477143 | 0.87 | KCNE1 (0.49) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8477178 | 0.86 | KCNE1 (0.46) | KCNE1KCNQ1ALDH1A1MAPTHTT | |
| SCHEMBL8481843 | 0.86 | KCNE1 (0.52) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8476683 | 0.84 | KCNE1 (0.46) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8481853 | 0.84 | KCNE1 (0.54) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8476715 | 0.83 | KCNE1 (0.45) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8476706 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8481785 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8306392 | 0.81 | KCNE1 (0.43) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL7469113 | 0.80 | ALDH1A1 (0.46) | KCNE1KCNQ1MAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |