Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633891 | 0.93 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL17362473 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL29799384 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL17362471 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL7201032 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL18935574 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL30212234 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL23967443 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL2653818 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 | |
| SCHEMBL30987468 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP1A2CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1233180-A | Treatment of the common cold or allergic rhinitis | LILLY CO ELI (US) | 1999-10-27 | — | — | CN | disclosed |
| US-5935992-A | TREATMENT OF MIGRAINE | ELI LILLY AND COMPANY (US) | 1999-08-10 | — | — | US | disclosed |