Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212234 | 1.00 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL18935574 | 0.96 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL23967443 | 0.94 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL30987468 | 0.94 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL2653818 | 0.94 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL2665681 | 0.91 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL9625796 | 0.91 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| Bicarbonate SCHEMBL14811674 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TSHRTDP1KMT2A | |
| SCHEMBL8477142 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1TSHRCHRM2OPRM1 | |
| SCHEMBL14075773 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180558-A | It is the method that one step of starting material constructs N- cyclobutyl phthalimide using imines | 桂林理工大学 | 2019-01-11 | — | — | CN | claimed |
| US-11673900-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAPAN TOBACCO INC. (JP) | 2023-06-13 | — | — | US | disclosed |
| US-20200216470-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | JAPAN TOBACCO INC. (JP) | 2020-07-09 | — | — | US | disclosed |
| CN-109180558-A | It is the method that one step of starting material constructs N- cyclobutyl phthalimide using imines | 桂林理工大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-109180558-A | It is the method that one step of starting material constructs N- cyclobutyl phthalimide using imines | 桂林理工大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-109180558-A | It is the method that one step of starting material constructs N- cyclobutyl phthalimide using imines | 桂林理工大学 | 2019-01-11 | — | — | CN | disclosed |
| WO-2017040606-A1 | ISOXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF PULMONARY DISEASES AND DISORDERS | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2017-03-09 | — | — | WO | disclosed |
| EP-1071645-A4 | PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1071645-A1 | PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-31 | — | — | EP | disclosed |
| US-6172118-B1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| WO-1999052847-A1 | PHOSPHODIESTERASE ISOENZYME DENOMINATED 4 (PDE 4) INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673900-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAK1, JAK3, JAK2 | ALDH1A1 1674/4885L3MBTL1 3776/4885TSHR 2651/4885 |
| US-20200216470-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF | JAK1, JAK3, JAK2 | ALDH1A1 1674/4885L3MBTL1 3776/4885TSHR 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.