Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066264 | 0.84 | MAPK1 (0.47) | ALDH1A1MAPK1HTTLMNAHPGD | |
| SCHEMBL24688169 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPK1HTTHPGDTSHR | |
| SCHEMBL8473107 | 0.82 | HTT (0.48) | ALDH1A1HTTCYP2C9CYP2C19HPGD | |
| SCHEMBL8473611 | 0.80 | HTT (0.58) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL8473182 | 0.77 | HPGD (0.61) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL13631426 | 0.73 | HPGD (0.71) | MAPK1HTTHPGDTSHRPOLB | |
| SCHEMBL24462094 | 0.73 | HPGD (0.39) | ALDH1A1MAPK1HTTLMNACYP2C9 | |
| SCHEMBL8472912 | 0.72 | HPGD (0.51) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL12067161 | 0.72 | CA12 (0.50) | ALDH1A1HTTCYP2C9CYP2C19HPGD | |
| SCHEMBL29332952 | 0.71 | MAPK1 (0.50) | ALDH1A1MAPK1HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |