Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472912 | 0.87 | HPGD (0.51) | HPGDTSHRALDH1A1HTTAPOBEC3A | |
| SCHEMBL24688169 | 0.85 | ALDH1A1 (0.59) | MAPK1HPGDTSHRALDH1A1HTT | |
| SCHEMBL8474666 | 0.84 | HPGD (0.63) | HPGDTSHRALDH1A1HTTAPOBEC3A | |
| SCHEMBL8475470 | 0.84 | HPGD (0.59) | HPGDTSHRALDH1A1HTTAPOBEC3A | |
| SCHEMBL8472289 | 0.84 | ALDH1A1 (0.48) | HPGDTSHRALDH1A1HTTAPOBEC3A | |
| SCHEMBL8477227 | 0.84 | ALDH1A1 (0.45) | MAPK1HPGDTSHRALDH1A1HTT | |
| SCHEMBL8478721 | 0.83 | HPGD (0.66) | HPGDTSHRALDH1A1HTTCA2 | |
| SCHEMBL8476172 | 0.83 | HPGD (0.66) | HPGDTSHRALDH1A1HTTCA2 | |
| SCHEMBL8475238 | 0.83 | HPGD (0.58) | HPGDTSHRALDH1A1HTTAPOBEC3A | |
| SCHEMBL8066284 | 0.81 | ALDH1A1 (0.45) | HPGDTSHRALDH1A1HTTAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005463-A1 | FURANSULFONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-06-07 | — | — | EP | disclosed |
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999009022-A1 | FURANSULFONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |