Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473472 | 0.80 | DRD2 (0.44) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL8477986 | 0.78 | DRD2 (0.44) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL7149529 | 0.71 | DRD2 (0.53) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL7150338 | 0.68 | DRD2 (0.51) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL8473649 | 0.66 | HTR2A (0.42) | SCDHTR2AHTR7ALDH1A1LMNA | |
| SCHEMBL3144674 | 0.66 | DRD2 (0.70) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL30102638 | 0.66 | DRD2 (0.70) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL3139830 | 0.65 | DRD2 (0.78) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL7147314 | 0.65 | CYP2D6 (0.54) | DRD2SLC6A4SCDOPRM1OPRD1 | |
| SCHEMBL7145335 | 0.65 | DRD2 (0.52) | DRD2SLC6A4SCDOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919788-A | PSYCHOLOGICAL DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1999-07-06 | — | — | US | disclosed |