Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 3/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 11/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477357 | 0.79 | KCNE1 (0.47) | KCNE1KCNQ1KCNA5TRPV1 | |
| SCHEMBL7479126 | 0.67 | KCNA5 (0.45) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL7479115 | 0.67 | KCNA5 (0.45) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL7479109 | 0.67 | KCNA5 (0.45) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL6276071 | 0.65 | KCNA5 (0.48) | KCNA5 | |
| SCHEMBL5868249 | 0.65 | KCNA5 (0.48) | KCNA5 | |
| SCHEMBL5868254 | 0.65 | KCNA5 (0.48) | KCNA5 | |
| SCHEMBL7473039 | 0.65 | KCNE1 (0.47) | KCNE1KCNQ1TRPV1 | |
| SCHEMBL7472250 | 0.63 | ABCC9 (0.61) | — | |
| SCHEMBL7472234 | 0.63 | ABCC9 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |