Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633486 | 0.90 | DPP4 (0.51) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL692993 | 0.85 | CYP2D6 (0.50) | OPRM1OPRL1OPRK1OPRD1CYP2D6 | |
| SCHEMBL13597006 | 0.84 | DPP4 (0.49) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL84788 | 0.83 | OPRM1 (0.44) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| Hydrochloric Acid SCHEMBL4159913 | 0.82 | OPRM1 (0.43) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL8473371 | 0.80 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1DPP4OPRM1OPRL1 | |
| SCHEMBL13597021 | 0.80 | DPP4 (0.61) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL18614900 | 0.79 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL18634599 | 0.79 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 | |
| SCHEMBL18614904 | 0.79 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1DPP4SLC6A9OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872115-A | COMPOUNDS FOR TREATMENT OF HYPERCHOLESTEROLEMIA, ISCHEMIC HEART DISEASE, CEREBROVASCULAR DISEASE OR ATHEROSCLEROSIS | GRELAN PHARMACEUTICAL CO. LTD. (JP) | 1999-02-16 | — | — | US | disclosed |