Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559 | 0.90 | AGTR1 (0.51) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL1810051 | 0.87 | AGTR1 (0.64) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL1810055 | 0.87 | AGTR1 (0.64) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL7272306 | 0.87 | AGTR1 (0.63) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL10057910 | 0.82 | AGTR1 (0.52) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8241866 | 0.82 | AGTR1 (0.52) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8383192 | 0.81 | AGTR1 (0.51) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL12655019 | 0.81 | LTB4R2 (0.53) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2032 | 0.81 | AGTR1 (0.66) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2033 | 0.81 | AGTR1 (0.66) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |