Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481255 | 0.88 | POLB (0.49) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL8473775 | 0.88 | MEN1 (0.47) | HTR4MEN1KMT2AATMTPSAB1 | |
| SCHEMBL8472966 | 0.88 | GSK3B (0.46) | HTR4MEN1KMT2AATMTPSAB1 | |
| SCHEMBL8474226 | 0.87 | ALDH1A1 (0.50) | HTR4ALDH1A1CCR2 | |
| SCHEMBL8477912 | 0.86 | IP6K1 (0.48) | MEN1KMT2AATMTPSAB1NPC1 | |
| SCHEMBL8473551 | 0.86 | DRD2 (0.43) | MEN1KMT2AATMTPSAB1DRD2 | |
| SCHEMBL8475037 | 0.86 | OPRL1 (0.40) | HTR4MEN1KMT2AATMTPSAB1 | |
| SCHEMBL8477606 | 0.85 | IP6K1 (0.47) | MEN1KMT2AATMTPSAB1NPC1 | |
| SCHEMBL8476749 | 0.84 | SCN7A (0.41) | HTR4MEN1KMT2AATMDRD2 | |
| SCHEMBL8474864 | 0.84 | NPY2R (0.43) | HTR4MEN1KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872115-A | COMPOUNDS FOR TREATMENT OF HYPERCHOLESTEROLEMIA, ISCHEMIC HEART DISEASE, CEREBROVASCULAR DISEASE OR ATHEROSCLEROSIS | GRELAN PHARMACEUTICAL CO. LTD. (JP) | 1999-02-16 | — | — | US | disclosed |