Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476480 | 1.00 | MEN1 (0.51) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL3651432 | 0.83 | MEN1 (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL20969294 | 0.83 | MEN1 (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL5146172 | 0.82 | MEN1 (0.58) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL5271778 | 0.82 | MEN1 (0.58) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL7149533 | 0.82 | MEN1 (0.58) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL1370500 | 0.80 | MEN1 (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL1370501 | 0.80 | MEN1 (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL8472603 | 0.80 | MEN1 (0.49) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL28295623 | 0.79 | MEN1 (0.51) | MEN1KMT2AHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990341-A | Diastereoselective synthesis hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |
| US-5587514-A | Diastereoselective synthesis of hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1995014655-A1 | DIASTEREOSELECTIVE SYNTHESIS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES | EMORY UNIVERSITY (US) | 1995-06-01 | — | — | WO | disclosed |