Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 1.00 |
| ▸ | GABRD | O14764 | 4/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 4/20 | 1.00 |
| ▸ | GABRB1 | P18505 | 4/20 | 1.00 |
| ▸ | GABRG2 | P18507 | 4/20 | 1.00 |
| ▸ | GABRB3 | P28472 | 4/20 | 1.00 |
| ▸ | GABRA5 | P31644 | 4/20 | 1.00 |
| ▸ | GABRA3 | P34903 | 4/20 | 1.00 |
| ▸ | GABRA2 | P47869 | 4/20 | 1.00 |
| ▸ | GABRB2 | P47870 | 4/20 | 1.00 |
| ▸ | GABRA4 | P48169 | 4/20 | 1.00 |
| ▸ | GABRE | P78334 | 4/20 | 1.00 |
| ▸ | GABRA6 | Q16445 | 4/20 | 1.00 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 1.00 |
| ▸ | GABRG3 | Q99928 | 4/20 | 1.00 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 1.00 |
| ▸ | QPCT | Q16769 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708991 | 0.87 | MEN1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13259767 | 0.83 | MEN1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9148162 | 0.82 | MEN1 (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3703230 | 0.81 | MEN1 (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29424233 | 0.81 | BACE1 (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Norartocarpetin SCHEMBL29435851 | 0.81 | BACE1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14464104 | 0.81 | BACE1 (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Norartocarpetin SCHEMBL1546435 | 0.81 | BACE1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22738310 | 0.80 | MEN1 (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Chrysin SCHEMBL44474 | 0.80 | MAPT (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004998-A | FLAVONOID 6,8-DIBROMOCHRYSIN | UNIVERSITY OF STRATHCLYDE (GB) | 1999-12-21 | — | — | US | disclosed |
| US-5756538-A | REDUCING THE SEDATIVE AND RELAXANT SIDE EFFECT | UNIVERSITY OF STRATHCLYDE (GB) | 1998-05-26 | — | — | US | disclosed |