Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478639 | 0.88 | MAPT (0.36) | ALDH1A1MAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL8482377 | 0.88 | L3MBTL1 (0.40) | MAPTKDM4EDRD4MEN1KMT2A | |
| SCHEMBL8477737 | 0.88 | MAPT (0.40) | ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8483053 | 0.88 | MAPT (0.35) | ALDH1A1MAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL8478027 | 0.88 | KCNH2 (0.41) | MAPTDRD4LMNAKMT2AMAPK1 | |
| SCHEMBL8478330 | 0.87 | KDM1A (0.39) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8478303 | 0.85 | ITGB3 (0.39) | MAPTLMNAMEN1KMT2AITGB3 | |
| SCHEMBL8482814 | 0.84 | MAPT (0.33) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8482577 | 0.82 | S1PR1 (0.36) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8478858 | 0.80 | GAA (0.42) | MAPTHTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5871709-A | TETRAAZACYCLODODECANE COMPOUNDS SUBSTITUTED WITH ALKYL CARBOXY COMPOUNDS FOR CARDIOVASCULAR DISORDERS AND BRAIN TUMORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |