Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24324236 | 0.90 | TRPM8 (0.56) | CTRB1TRPM8ATMCTSKCTSL | |
| SCHEMBL7698179 | 0.90 | TRPM8 (0.56) | CTRB1TRPM8ATMCTSKCTSL | |
| SCHEMBL4910315 | 0.90 | TRPM8 (0.56) | CTRB1TRPM8ATMCTSKCTSL | |
| SCHEMBL5413813 | 0.90 | TRPM8 (0.56) | CTRB1TRPM8ATMCTSKCTSL | |
| SCHEMBL3029758 | 0.85 | CTSK (0.55) | CTRB1ATMCTSKCTSLCTSS | |
| SCHEMBL2577831 | 0.80 | SPPL2A (0.53) | CTRB1TRPM8CTSKCTSLSPPL2A | |
| SCHEMBL2582361 | 0.80 | SPPL2A (0.53) | CTRB1TRPM8CTSKCTSLSPPL2A | |
| SCHEMBL4908808 | 0.80 | SPPL2A (0.53) | CTRB1TRPM8CTSKCTSLSPPL2A | |
| SCHEMBL25465632 | 0.79 | TRPM8 (0.66) | CTRB1TRPM8ATMCTSKCTSL | |
| SCHEMBL13219392 | 0.79 | TRPM8 (0.59) | CTRB1TRPM8ATMCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985870-A | TREATING HIV INFECTIONS | G.D. SEARLE & CO. (US) | 1999-11-16 | — | — | US | disclosed |