Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 11/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132935 | 0.88 | CA1 (0.46) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL7555114 | 0.87 | CA1 (0.44) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL6132559 | 0.86 | L3MBTL1 (0.49) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL8479516 | 0.86 | L3MBTL1 (0.49) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL9242103 | 0.86 | L3MBTL1 (0.49) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL8480340 | 0.86 | CA1 (0.64) | CA1CA2CA4CA9HCRTR1 | |
| SCHEMBL7555118 | 0.85 | CA1 (0.44) | CA1CA2CA4CA9HCRTR1 | |
| Hydrochloric Acid SCHEMBL9240138 | 0.85 | L3MBTL1 (0.48) | CA1CA2CA4CA9HCRTR1 | |
| Hydrochloric Acid SCHEMBL8476515 | 0.85 | L3MBTL1 (0.48) | CA1CA2CA4CA9HCRTR1 | |
| Fumaric Acid SCHEMBL7554500 | 0.81 | TACR1 (0.46) | CA1CA2CA4CA9HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883098-A | USED AS TACHYKININ ANTAGONISTS IN THE TREATMENT OF RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND INFLAMMATORY DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |