Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 12/20 | 0.59 |
| ▸ | EDNRB | P24530 | 11/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221292 | 0.87 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8473321 | 0.86 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL8479975 | 0.86 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8478164 | 0.85 | HSD11B1 (0.49) | EDNRAEDNRBP2RY1HSD11B1 | |
| SCHEMBL27490281 | 0.84 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7849820 | 0.80 | P2RY1 (0.80) | EDNRAEDNRBP2RY1 | |
| SCHEMBL7217788 | 0.80 | EDNRA (0.73) | EDNRAEDNRBP2RY1 | |
| SCHEMBL9063401 | 0.78 | EDNRA (0.74) | EDNRAEDNRBP2RY1 | |
| SCHEMBL7224060 | 0.78 | EDNRA (0.74) | EDNRAEDNRBP2RY1 | |
| SCHEMBL8477980 | 0.77 | HSD11B1 (0.53) | EDNRAEDNRBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |