Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484334 | 0.82 | HPGD (0.66) | HPGDTSHRPARP1KDM4EPOLB | |
| SCHEMBL7491844 | 0.76 | KDM4E (0.48) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6783276 | 0.75 | HPGD (0.60) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL30273080 | 0.75 | HPGD (0.60) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL25607486 | 0.75 | PARP1 (0.35) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL14355033 | 0.74 | TSHR (0.50) | HPGDTSHRCHEK1KDM4EPOLB | |
| SCHEMBL7484251 | 0.73 | HPGD (0.45) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7486485 | 0.72 | HPGD (0.43) | HPGDPARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL26596941 | 0.71 | GPR17 (0.35) | HPGDPARP1DAO | |
| SCHEMBL31487035 | 0.71 | GPR17 (0.35) | HPGDPARP1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914402-A | Process for preparing 1-aryl-4-oxopyrrolo 3,2-c! quinoline derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-06-22 | — | — | US | disclosed |
| US-5807851-A | MUSCLE RELAXANTS; NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR RT. (HU) | 1998-09-15 | — | — | US | disclosed |
| EP-0853622-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997044342-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-27 | — | — | WO | disclosed |