Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486485 | 0.91 | HPGD (0.43) | HPGDKDM4EPARP1PIK3CGADORA3 | |
| SCHEMBL7491844 | 0.84 | KDM4E (0.48) | HPGDKDM4EPARP1PIK3CGCYP1A2 | |
| SCHEMBL8484334 | 0.80 | HPGD (0.66) | HPGDKDM4EPARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8478795 | 0.73 | HPGD (0.44) | HPGDKDM4EPARP1CYP1A2CYP2D6 | |
| SCHEMBL7488966 | 0.70 | ADRA1D (0.42) | KDM4EADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7495661 | 0.70 | KDM4E (0.48) | HPGDKDM4EPARP1ADRA1DADRA1A | |
| SCHEMBL25187586 | 0.68 | PARP1 (0.34) | HPGDPARP1CYP1A2CYP2D6ALPG | |
| SCHEMBL7491401 | 0.68 | ADRA1A (0.40) | PARP1ADRA1DADRA1AADRA1BPIK3CG | |
| SCHEMBL6783276 | 0.67 | HPGD (0.60) | HPGDKDM4EPARP1CYP1A2CYP2D6 | |
| SCHEMBL30273080 | 0.67 | HPGD (0.60) | HPGDKDM4EPARP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966466-B1 | PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RES INST CHEM TECH (KR) | 2002-07-03 | — | — | EP | disclosed |
| US-6011044-A | ANTIULCER AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-04 | — | — | US | disclosed |