Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480854 | 1.00 | HDAC6 (0.47) | HDAC6ATMKMT2ACYP2C19MEN1 | |
| SCHEMBL8475813 | 0.85 | MEN1 (0.48) | KMT2ACYP2C19MEN1GAA | |
| SCHEMBL7032233 | 0.80 | HDAC6 (0.54) | HDAC6ATMKMT2ACYP2C19TDP1 | |
| SCHEMBL7033149 | 0.80 | HDAC6 (0.54) | HDAC6ATMKMT2ACYP2C19TDP1 | |
| SCHEMBL8481433 | 0.78 | KMT2A (0.57) | KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8477666 | 0.77 | KMT2A (0.56) | KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6700970 | 0.77 | KMT2A (0.56) | KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7969482 | 0.77 | KMT2A (0.56) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL8479106 | 0.75 | KMT2A (0.38) | ATMKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6701567 | 0.72 | ATM (0.37) | ATMKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |