Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033149 | 1.00 | HDAC6 (0.54) | HDAC6ITGB3ITGA2BATMTDP1 | |
| SCHEMBL7028100 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BKMT2ACYP2C19 | |
| SCHEMBL7028357 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BKMT2ACYP2C19 | |
| SCHEMBL8480854 | 0.80 | HDAC6 (0.47) | HDAC6ATMTDP1KMT2ACYP2C19 | |
| SCHEMBL8478796 | 0.80 | HDAC6 (0.47) | HDAC6ATMTDP1KMT2ACYP2C19 | |
| SCHEMBL7031835 | 0.77 | ITGB3 (0.66) | ITGB3ITGA2BKMT2ACYP2C19 | |
| SCHEMBL5649043 | 0.77 | HDAC6 (0.61) | HDAC6TDP1CYP2C19 | |
| Hydrochloric Acid SCHEMBL6700967 | 0.76 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL7969479 | 0.76 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL6700973 | 0.76 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823898-B1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| EP-0823898-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996033976-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-31 | — | — | WO | disclosed |