Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480854 | 0.85 | HDAC6 (0.47) | MEN1KMT2AGAACYP2C19 | |
| SCHEMBL8478796 | 0.85 | HDAC6 (0.47) | MEN1KMT2AGAACYP2C19 | |
| SCHEMBL8481433 | 0.83 | KMT2A (0.57) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6700970 | 0.82 | KMT2A (0.56) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7969482 | 0.82 | KMT2A (0.56) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8477666 | 0.82 | KMT2A (0.56) | MEN1KMT2A | |
| SCHEMBL7028357 | 0.79 | ITGB3 (0.48) | MEN1KMT2AGAATSHRCYP2C19 | |
| SCHEMBL7028100 | 0.79 | ITGB3 (0.48) | MEN1KMT2AGAATSHRCYP2C19 | |
| SCHEMBL8479106 | 0.77 | KMT2A (0.38) | KMT2AALDH1A1 | |
| SCHEMBL8523438 | 0.74 | PTGDR2 (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |