Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478284 | 0.88 | GCGR (0.38) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL8479432 | 0.85 | GCGR (0.41) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL8479567 | 0.82 | GCGR (0.40) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL8478733 | 0.80 | ESR2 (0.43) | ESR1ESR2PTGS2HEXAHEXB | |
| SCHEMBL8477832 | 0.75 | TP53 (0.34) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL8480800 | 0.75 | ACHE (0.35) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL27860186 | 0.74 | ESR1 (0.47) | GCGRESR1ESR2PTGS1PTGS2 | |
| SCHEMBL8474730 | 0.71 | PDE4B (0.46) | GCGRPTGS1PTGS2KDM4EDHFR | |
| SCHEMBL8477631 | 0.71 | PDE4B (0.42) | PTGS1PTGS2KDM4EDHFRHEXA | |
| SCHEMBL8478931 | 0.70 | ESR1 (0.41) | ESR1ESR2PTGS2KDM4EHEXA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |