Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479476 | 0.86 | KDM4E (0.36) | ACHEKDM4ERCE1DHFRSMN1; SMN2 | |
| SCHEMBL8480278 | 0.76 | ACHE (0.38) | ACHEKDM4EPTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL8479044 | 0.75 | GCGR (0.40) | KDM4EPTGS1PTGS2DHFRHEXA | |
| SCHEMBL8477832 | 0.75 | TP53 (0.34) | KDM4EPTGS1PTGS2DHFRHEXA | |
| SCHEMBL8477631 | 0.75 | PDE4B (0.42) | KDM4EPTGS1PTGS2DHFRHEXA | |
| SCHEMBL8474843 | 0.72 | KDM4E (0.39) | ACHEKDM4EPTGS2SMN1; SMN2MEN1 | |
| SCHEMBL8482098 | 0.72 | PDE4B (0.56) | KDM4ERCE1ALDH1A1GAAMAPT | |
| SCHEMBL8478736 | 0.72 | PTGS1 (0.33) | KDM4EPTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL8478725 | 0.71 | TP53 (0.35) | ACHEKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL8474890 | 0.71 | PDE4B (0.54) | KDM4ERCE1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |