SCHEMBL848003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL849340	0.85	HPGD (0.59)	HPGDTSHRALDH1A1TP53MGLL
	SCHEMBL848798	0.84	HPGD (0.77)	HPGDTSHRALDH1A1TP53MGLL
	SCHEMBL9300442	0.84	HPGD (0.71)	HPGDTSHRALDH1A1TP53MGLL
	SCHEMBL2376496	0.83	HPGD (0.77)	HPGDTSHRALDH1A1TP53CNR2
	SCHEMBL2378485	0.83	HPGD (0.77)	HPGDTSHRALDH1A1TP53CNR2
	SCHEMBL12068505	0.82	GLA (0.55)	HPGDALDH1A1TP53KMT2AGLA
	SCHEMBL2378109	0.81	HPGD (0.67)	HPGDTSHRALDH1A1KMT2AGLA
	SCHEMBL850574	0.79	HSP90AA1 (0.59)	HPGDTSHRALDH1A1TP53MGLL
	SCHEMBL24556567	0.78	AKR1C1 (0.59)	HPGDTSHRALDH1A1TP53MGLL
	SCHEMBL2376824	0.78	HPGD (0.55)	HPGDTSHRALDH1A1TP53MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.